Vitamin D3 1 mil IU/G

High-Potency Vitamin D3 for Skin Repair and Barrier Support

INCI Name: Cholecalciferol, Zea Mays (Corn) Oil OR Cholecalciferol, Helianthus Annuus (Sunflower) Seed Oil

A high-potency, oil-soluble active featuring Cholecalciferol (Vitamin D3) at 1 million IU per gram in a stable carrier oil. This essential vitamin plays a critical role in skin health by modulating cellular turnover, strengthening the skin’s natural barrier, and providing potent anti-inflammatory benefits. It is an ideal ingredient for formulations targeting skin repair, reducing redness, and supporting overall skin resilience and health.

Solubility Notes:

Oil-soluble. Incorporate into the oil phase of formulations. Protect from heat and light during processing.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Barrier Repair Creams

Strengthens the stratum corneum and supports lipid barrier integrity in creams for compromised or sensitive skin.
Soothing & Anti-Inflammatory Serums

Effectively calms redness and irritation in targeted serums, helping to reduce the signs of inflammatory skin conditions.
Anti-Aging & Regenerative Night Creams

Promotes healthy cell differentiation and repair overnight, helping to minimize the appearance of fine lines and improve skin texture.
Scalp Health Treatments

Soothes dry, flaky, and irritated scalps by regulating cell turnover and reducing inflammation in hair serums and treatments.
Protective Body Lotions

Enhances the skin's natural defense mechanisms and provides antioxidant benefits in daily body care products.
Post-Procedure & Calming Formulas

Ideal for use in formulations designed to soothe skin and accelerate recovery after professional treatments.

Performance & Formulation Insights for Vitamin D3

How Vitamin D3 Works

Cholecalciferol, the active form of Vitamin D3, is a pro-hormone that plays a vital role in skin homeostasis. Topically applied, it interacts with Vitamin D Receptors (VDR) present in skin cells, particularly keratinocytes. This interaction helps regulate cellular proliferation and differentiation, ensuring a healthy and orderly skin cell life cycle. By promoting the maturation of keratinocytes, Vitamin D3 strengthens the epidermal barrier, reducing transepidermal water loss (TEWL) and improving the skin’s resilience. Furthermore, it exhibits powerful immunomodulatory and anti-inflammatory effects, helping to calm redness and irritation associated with various skin conditions.

Formulation Guidelines

This Vitamin D3 active is provided as a concentrated, oil-based solution for excellent stability and ease of use. The recommended usage rate is between 0.1% and 1.0%. As an oil-soluble ingredient, it should be incorporated into the oil phase of your formulation. Due to the sensitivity of Vitamin D3 to heat, light, and oxidation, add it during the cool-down phase at temperatures below 40°C (104°F). To ensure maximum stability in the final product, formulate within a pH range of 4.5–6.5 and consider using opaque or UV-protective packaging. The inclusion of an antioxidant like Vitamin E (Tocopherol) can further protect the integrity of Cholecalciferol.

Key Formulation Benefits

Strengthens Epidermal Barrier: Clinically recognized for its role in regulating cell turnover, which helps fortify the skin’s protective barrier and improve moisture retention.
Potent Anti-Inflammatory: Effectively soothes skin and reduces visible redness and irritation, making it ideal for sensitive or compromised skin formulations.
Supports Skin Immunity: Modulates the skin’s innate immune response, helping to maintain a healthy and balanced micro-environment.
Antioxidant Protection: Helps neutralize free radical damage, protecting the skin from environmental stressors and premature aging.
Oil-Soluble & Stable: Supplied in a carrier oil to protect the active from degradation and ensure easy incorporation into anhydrous and emulsion-based systems.
Versatile Application: Suitable for a wide range of products targeting skin health, from anti-aging and barrier repair to scalp care and soothing treatments.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Barrier Repair, Hair & Scalp Care, Moisturizing & Hydration, Scalp Health, Soothing & Anti-Inflammatory
INCI Name	Cholecalciferol, Zea Mays (Corn) Oil OR Cholecalciferol, Helianthus Annuus (Sunflower) Seed Oil
Usage Rate	0.1%-1%
Active Type	Vitamin D, Vitamins & Derivatives
Solubility	Oil-Soluble
Application Area	Body, Face, Scalp
Physical Form	Oil
Certifications	Non-GMO

Frequently Asked Questions About Vitamin D3 1 mil IU/G

The recommended usage rate for this 1 million IU/G concentrate is 0.1% to 1.0% in the final formulation.

It primarily works by binding to Vitamin D receptors in skin cells to regulate cell growth, strengthen the skin barrier, reduce inflammation, and provide antioxidant protection.

Yes. Vitamin D3 is generally compatible with other actives. When formulating with retinol, both can work synergistically to promote healthy cell turnover. It is also compatible with most Vitamin C derivatives and antioxidants.

For maximum stability, it is recommended to formulate within a skin-friendly pH range of 4.5 to 6.5.

Yes, Cholecalciferol is sensitive to high temperatures, UV light, and oxygen. It should be added during the cool-down phase of formulation, and finished products should be in opaque or UV-protective packaging.

Absolutely. Its ability to regulate keratinocyte proliferation and reduce inflammation makes it an excellent active for soothing dry, itchy, or flaky scalps.

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