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Sigmedia

Bioactive Lipid Messenger for Skin Rejuvenation and Stress Defense

INCI Name: Water, Butylene Glycol, Polysorbate 80, Lecithin, Dipropylene Glycol, Phytosphingosine Phosphate, 1,2-Hexanediol, Caprylyl Glycol

Sigmedia is an advanced, pre-solubilized complex featuring Phytosphingosine Phosphate—a bioactive, skin-identical lipid messenger. It helps fortify the skin barrier, soothe visible signs of stress, and support cellular vitality for a rejuvenated, resilient complexion. Ideal for anti-aging, anti-stress, and barrier-repair formulations across face, body, and sun care.

Solubility Notes:

Water-dispersible liquid. Add to the water phase or during cool-down (<40°C / 104°F). Generally stable in pH 4.5–7.0 and compatible with common actives.

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Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

  • Barrier Repair Creams
    Strengthens the skin’s protective lipid barrier to reduce TEWL and enhance resilience.
  • Anti-Stress & Calming Serums
    Visibly soothes irritation and redness from environmental stressors; ideal for sensitive or compromised skin.
  • Rejuvenating Night Treatments
    Supports overnight renewal for a revitalized, smoother-looking complexion by morning.
  • Advanced Anti-Aging Moisturizers
    Promotes cellular vitality and helps maintain firmness and elasticity for youthful-looking skin.
  • After-Sun & Post-Treatment Care
    Calms visible redness and supports recovery after sun exposure or cosmetic procedures.
  • Protective Day Creams & Lotions
    Reinforces daily defenses against pollution and other external aggressors.

Performance & Formulation Insights for Sigmedia

How Phytosphingosine Phosphate Works

Sigmedia centers on Phytosphingosine Phosphate, a phosphorylated derivative of a skin-identical lipid. As a bioactive lipid messenger, it communicates with skin cells to help regulate key processes involved in barrier integrity, cellular vitality, and the skin’s response to external stressors. By supporting the synthesis and organization of essential barrier lipids (including ceramides) and helping modulate pro-inflammatory mediators, it reinforces the skin’s natural defenses, calms visible redness and irritation, and promotes a smoother, more resilient complexion. The inclusion of lecithin and polysorbate in this pre-solubilized system enhances bioavailability and ease of incorporation in water-based formulas.

Formulation Guidelines

Supplied as an easy-to-use aqueous solution, Sigmedia can be added to the water phase of emulsions, gels, and serums. For optimal performance, introduce during the cool-down phase below 40°C (104°F) with gentle mixing. It is broadly compatible with common cosmetic actives (e.g., hyaluronic acid, niacinamide, vitamin C derivatives, peptides) and is stable within typical skin-care pH ranges (approximately pH 4.5–7.0). Recommended use level is 1–5%, depending on the desired activity and product type.

Key Formulation Benefits

  • Supports Barrier Integrity: Helps reinforce the skin’s lipid matrix and reduce transepidermal water loss for improved resilience.
  • Anti-Stress & Soothing: Assists in calming visible redness and discomfort associated with environmental and lifestyle stressors.
  • Cell Vitalization: Acts as a biological messenger to support healthy cellular function for a revitalized, rejuvenated appearance.
  • Enhanced Skin Defense: Strengthens the skin’s natural protective mechanisms against daily aggressors, including pollution.
  • Versatile & Formulator-Friendly: Pre-solubilized liquid integrates seamlessly into water-based systems without complex processing.
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Benefits
Anti-Aging & Anti-Wrinkle, Barrier Repair, Moisturizing & Hydration, Pollution Defense, Skin Elasticity, Soothing & Anti-Inflammatory
INCI Name
Water, Butylene Glycol, Polysorbate 80, Lecithin, Dipropylene Glycol, Phytosphingosine Phosphate, 1,2-Hexanediol, Caprylyl Glycol
Usage Rate
1%-5%
Active Type
Ceramides & Lipids
Solubility
Water-Soluble
Application Area
Body, Face
Physical Form
Liquid/Solution
Certifications
Cruelty-Free, Vegan

Frequently Asked Questions About Sigmedia

Sigmedia leverages Phytosphingosine Phosphate, a bioactive lipid messenger, to help regulate inflammatory pathways, support barrier lipid organization, and promote healthy cellular function for improved skin resilience and comfort.
Use 1–5% in finished formulations, selecting lower levels for daily maintenance products and higher levels for targeted or intensive treatments.
By helping modulate the skin’s response to external aggressors and reinforcing the barrier, Sigmedia reduces visible signs of stress such as redness and discomfort while improving overall resilience.
Yes. It is generally compatible and can complement potentially sensitizing actives by helping soothe skin and support barrier function.
Add to the water phase or during the cool-down phase below 40°C (104°F) with gentle mixing to preserve integrity.
Its pre-solubilized system with lecithin and polysorbate improves bioavailability and ease of formulation, delivering the benefits of Phytosphingosine Phosphate efficiently in aqueous formats.

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Sigmedia

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