Hydroderma-SE

Advanced Bio-Ferment for Intense Hydration and Skin Regeneration

INCI Name: Aureobasidium Pullulans Ferment Extract, Propanediol, Butylene glycol, 1,2-Hexanediol, Glycoprotein, Disodium EDTA

Hydroderma-SE is a high-performance biotech active derived from the fermentation of Aureobasidium pullulans. Rich in beta-glucans, glycoproteins, and natural polysaccharides, it delivers deep hydration, significant soothing, and supports skin regeneration. Its film-forming properties provide a subtle tightening effect and help lock in moisture, making it ideal for advanced anti-aging, moisturizing, and barrier repair formulations.

Solubility Notes:

Water-soluble, add to the water phase or during the cool-down phase of formulation below 40 °C.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Hydrating Serums & Essences

Delivers a concentrated dose of beta-glucans for deep, lasting hydration that plumps skin and reduces the appearance of fine lines.
Soothing & Calming Treatments

Effectively reduces redness and irritation, ideal for sensitive skin or post-procedure care products.
Barrier Repair Creams

Strengthens the skin's natural defenses and helps restore a healthy lipid barrier to prevent moisture loss.
Anti-Aging Moisturizers

Supports skin regeneration and provides antioxidant protection to combat signs of premature aging in daily-use creams.
Sheet Masks & Wash-Off Masks

Provides an intensive infusion of moisture and soothing actives for an immediate revitalizing and calming effect.
Hydrating Primers & Foundations

Creates a smooth, hydrated canvas for makeup application while delivering continuous skincare benefits throughout the day.

Performance & Formulation Insights for Hydroderma-SE

How Hydroderma-SE Works

Hydroderma-SE harnesses the power of biotechnology through the fermentation of the yeast-like fungus Aureobasidium pullulans. This controlled process yields a nutrient-rich filtrate concentrated in beta-glucans, glycoproteins, and protective polysaccharides that work synergistically to hydrate, soothe, and support skin regeneration.

Beta-Glucans: Exceptional humectants that bind and retain water for deep, lasting hydration. They also help modulate the skin’s natural immune response to visibly reduce redness and irritation.
Pullulan: A naturally occurring polysaccharide formed during fermentation that creates a thin, flexible, breathable film on the skin. This film provides an immediate, subtle tightening effect and significantly reduces TEWL to lock in moisture.
Glycoproteins & Metabolites: Support cellular communication and key enzymatic functions to aid skin repair and regeneration for a healthier, more resilient appearance.

Formulation Guidelines

Hydroderma-SE is a user-friendly aqueous solution for effortless incorporation into serums, emulsions, gels, and masks. To preserve bioactivity, add during the cool-down phase at temperatures below 40 °C (104 °F). It is stable in a cosmetic pH range of approximately 4.0–7.0.

This active is highly compatible with hyaluronic acid, niacinamide, peptides, ceramides, and botanical extracts for synergistic, multi-functional formulas. Typical usage is 2–5% for daily hydration and up to 10% for intensive soothing, barrier repair, or treatment products.

Key Formulation Benefits

Superior Hydration: Provides deep, long-lasting moisture with a high content of beta-glucans that can outperform traditional humectants.
Clinically-Proven Soothing: Calms irritated and sensitive skin, reducing visible redness and discomfort.
Barrier Reinforcement: Supports a healthy skin barrier and microbiome for improved resilience and reduced moisture loss.
Instant Smoothing Effect: Film-forming pullulan delivers a perceivable tightening and smoothing upon application.
Antioxidant Protection: Fermentation-derived metabolites help neutralize free radicals and defend against environmental stressors.
Clean & Biotech Origin: Fermented, science-forward active that aligns with consumer demand for gentle, effective, and advanced skincare ingredients.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Barrier Repair, Deep Hydration, Moisturizing & Hydration, Skin Elasticity, Soothing & Anti-Inflammatory
INCI Name	Aureobasidium Pullulans Ferment Extract, Propanediol, Butylene glycol, 1,2-Hexanediol, Glycoprotein, Disodium EDTA
Usage Rate	2%-10%
Active Type	Biotech/Fermentation Actives, Fermented Ingredients, β-Glucans
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Non-GMO, Vegan

Frequently Asked Questions About Hydroderma-SE

For general hydrating and daily-use products, 2–5% is effective. For intensive treatments, soothing serums, or barrier repair creams, use 5–10%.

Both are excellent hydrators, but beta-glucans in Hydroderma-SE also provide potent soothing benefits and can deliver moisture at deeper levels. They can be combined for synergistic hydration.

Yes. Its primary functions are to soothe and hydrate, making it ideal for sensitive, reactive, or compromised skin.

Beta-glucans are the key components, responsible for its hydrating, soothing, and skin-regenerating effects.

Yes. Add during the cool-down phase at temperatures below 40 °C (104 °F) to preserve bioactivity.

Yes. In leave-ons like serums and creams, it delivers sustained hydration and soothing; in rinse-offs like cleansers or masks, it helps mitigate irritation and leaves skin soft and hydrated.

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