Glabridin 40%

Q: What is the recommended usage rate for Glabridin 40%?

The recommended concentration is between 0.1% and 0.5% in the final formulation, depending on the desired intensity of the brightening effect.

Q: How do I properly dissolve Glabridin 40% in my formula?

Glabridin 40% is a powder that should be pre-dissolved in a glycol, such as Butylene Glycol or Propylene Glycol, before being added to your formulation. It is insoluble in water and has poor solubility in oil.

Q: How does Glabridin compare to other brightening agents like Vitamin C or Arbutin?

Glabridin works primarily by potently inhibiting the tyrosinase enzyme, which is a highly effective mechanism for preventing pigmentation. It can be used synergistically with actives like Vitamin C (an antioxidant that also inhibits tyrosinase) and Arbutin (a tyrosinase substrate competitor) for a multi-pathway approach to skin brightening.

Q: Is Glabridin 40% suitable for leave-on products?

Yes, it is perfectly suited for all types of leave-on products, including serums, creams, lotions, and spot treatments, where its long-term benefits can be most effective.

Q: What is the optimal pH range for formulations containing Glabridin 40%?

This active performs best and remains stable in formulations with a pH range between 4.5 and 6.5.

Q: Can this ingredient help with post-acne marks?

Yes, due to its combined anti-inflammatory and tyrosinase-inhibiting properties, Glabridin 40% is highly effective at addressing the post-inflammatory hyperpigmentation (PIH) that appears as dark marks after acne blemishes heal.

High-Purity Licorice Root Extract for Advanced Skin Brightening

INCI Name: Glycyrrhiza Glabra (Licorice) Root Extract

Glabridin 40% is a premium, high-potency powder extract from licorice root, standardized to a minimum of 40% Glabridin. As a potent tyrosinase inhibitor, it effectively interrupts the melanin synthesis pathway to visibly reduce hyperpigmentation, dark spots, and uneven skin tone. Its strong antioxidant and anti-inflammatory properties make it a multifunctional active ideal for creating advanced skin brightening and clarifying formulations.

Solubility Notes:

Insoluble in water and most oils. Soluble in glycols (e.g., Butylene Glycol, Propylene Glycol). Predissolve in a suitable solvent before adding to the formulation; add premix during cool-down (<40°C).

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Brightening & Dark Spot Serums

Delivers a concentrated dose of Glabridin to effectively target and fade discoloration and post-inflammatory hyperpigmentation.
Even-Tone Face Creams & Moisturizers

Incorporates into daily-use creams to promote a consistently bright, luminous, and even complexion over time.
Targeted Spot Treatments

Provides intensive action in concentrated formulas designed to be applied directly to age spots, sun spots, and acne marks.
Brightening Eye Creams

Gently helps to diminish the appearance of periorbital hyperpigmentation (dark circles) for a more rested look.
Corrective Facial Masks

Boosts the efficacy of wash-off or leave-on masks aimed at improving overall skin clarity and radiance.
Soothing & Brightening Toners

Combines anti-inflammatory and brightening benefits in liquid formulations for sensitive or blemish-prone skin.

Performance & Formulation Insights for Glabridin 40%

How Glabridin Brightens and Calms the Skin

Glabridin, the principal isoflavonoid in licorice root, is renowned for its powerful skin-brightening capabilities. Its primary mechanism of action is the potent inhibition of tyrosinase, the key enzyme responsible for converting tyrosine into melanin. By effectively blocking this enzymatic activity, Glabridin prevents the formation of new melanin, leading to a visible reduction in dark spots and a more even skin tone. Beyond its depigmenting effects, Glabridin is also a highly effective antioxidant, scavenging free radicals that contribute to premature aging and skin damage. Furthermore, it exhibits significant anti-inflammatory properties, helping to soothe redness and irritation, making it an excellent choice for sensitive skin types or for addressing post-inflammatory hyperpigmentation.

Formulation Guidelines for Optimal Performance

Glabridin 40% is a lipophilic powder with specific solubility requirements. It is insoluble in water and has very low solubility in common cosmetic oils. To ensure proper incorporation, it must be pre-dissolved in a suitable solvent such as Butylene Glycol, Propylene Glycol, or Pentylene Glycol, gently warming if necessary. Once a clear solution is achieved, this premix can be added to the oil phase of an emulsion or during the cool-down phase (below 40°C). The recommended usage rate is 0.1% to 0.5% for effective results. Glabridin 40% is stable within a typical cosmetic pH range of 4.5 to 6.5. For enhanced brightening, it can be synergistically combined with other actives like Vitamin C derivatives, Niacinamide, and Alpha Arbutin.

Key Formulation Benefits

Potent Tyrosinase Inhibition: Offers one of the most powerful natural mechanisms for controlling hyperpigmentation, often compared to hydroquinone but with a superior safety profile.
Multi-Functional Efficacy: Provides skin brightening, antioxidant protection, and anti-inflammatory benefits from a single botanical source.
High-Purity Active: Standardized to 40% Glabridin, ensuring consistent and reproducible results in final formulations.
Excellent for Sensitive Skin: Its calming properties make it ideal for brightening products aimed at users with sensitive or redness-prone skin.
Clinically Recognized: Glabridin is a well-researched and documented molecule for cosmetic skin brightening and depigmenting applications.
Natural & Vegan: A plant-derived active that meets consumer demand for clean and conscious beauty ingredients.

Heading #1
Benefits	Antioxidants, Brightening & Skin Lightening, Dark Spot Reduction, Soothing & Anti-Inflammatory, Tyrosinase Inhibition
INCI Name	Glycyrrhiza Glabra (Licorice) Root Extract
Usage Rate	0.1%-0.5%
Active Type	Botanical Extracts & Phytoactives, Licorice Derivatives
Solubility	Oil-Soluble
Application Area	Body, Eye, Face, Lip, Nail
Physical Form	Powder
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About Glabridin 40%

The recommended concentration is between 0.1% and 0.5% in the final formulation, depending on the desired intensity of the brightening effect.

Glabridin 40% is a powder that should be pre-dissolved in a glycol, such as Butylene Glycol or Propylene Glycol, before being added to your formulation. It is insoluble in water and has poor solubility in oil.

Glabridin works primarily by potently inhibiting the tyrosinase enzyme, which is a highly effective mechanism for preventing pigmentation. It can be used synergistically with actives like Vitamin C (an antioxidant that also inhibits tyrosinase) and Arbutin (a tyrosinase substrate competitor) for a multi-pathway approach to skin brightening.

Yes, it is perfectly suited for all types of leave-on products, including serums, creams, lotions, and spot treatments, where its long-term benefits can be most effective.

This active performs best and remains stable in formulations with a pH range between 4.5 and 6.5.

Yes, due to its combined anti-inflammatory and tyrosinase-inhibiting properties, Glabridin 40% is highly effective at addressing the post-inflammatory hyperpigmentation (PIH) that appears as dark marks after acne blemishes heal.

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