BIO-Placenta

High-Performance Growth Factor Complex for Total Skin Rejuvenation

INCI Name: Water, Lecithin, Acetyl glutamine, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-11, Bacillus/ Folic Acid Ferment Extract, Sodium Hyaluronate, Caprylyl Glycol, Butylene Glycol, 1,2-Hexanediol

BIO-Placenta is an advanced, clinically-studied active that replicates the benefits of human placenta using five synthesized growth factors (EGF, IGF-1, acidic FGF, basic FGF, VEGF), fermented Vitamin B9, and Acetyl Glutamine. This powerful biomimetic complex accelerates skin renewal, boosts collagen synthesis, and improves elasticity. Its liposomal delivery system ensures optimal penetration, making it a premier choice for high-performance anti-aging serums, creams, and regenerative treatments.

Solubility Notes:

Water-soluble. Incorporate into the water phase or during the cool-down phase below 40°C (104°F). Stable between pH 4.5 and 7.0.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

High-Performance Anti-Aging Serums

Delivers a concentrated dose of five synergistic growth factors to dramatically reduce the appearance of fine lines and deep wrinkles.
Firming & Lifting Face Creams

Improves skin density and elasticity, providing a visible lifting and contouring effect in daily moisturizers.
Regenerative Night Treatments

Supports the skin's natural overnight repair processes to rejuvenate texture, tone, and overall radiance.
Eye Creams & Concentrates

Safely and effectively targets signs of aging in the delicate eye area, diminishing crow's feet and improving firmness.
Post-Procedure Skincare

Aids in skin recovery and renewal in formulations designed for use after cosmetic treatments like microneedling or peels.
Booster & Ampoule Products

Creates potent, targeted treatments that can be added to existing skincare routines for an intensive anti-aging boost.

Performance & Formulation Insights for BIO-Placenta

How BIO-Placenta Works

BIO-Placenta is a breakthrough in cosmetic biotechnology, delivering a synergistic complex of five biomimetic growth factors to rejuvenate the skin. Each growth factor plays a specific role: sh-Oligopeptide-1 (EGF) accelerates cell renewal; sh-Oligopeptide-2 (IGF-1) works with EGF to smooth wrinkles; sh-Polypeptide-1 (bFGF) and sh-Polypeptide-11 (aFGF) stimulate collagen and elastin to improve elasticity and firmness; and sh-Polypeptide-9 (VEGF) supports nutrient delivery to the skin. This potent blend is enhanced with fermented Folic Acid (Vitamin B9) for improved bioavailability and Acetyl Glutamine to boost cellular metabolism. Encapsulation in a lecithin-based liposomal system optimizes penetration and stability, ensuring the actives reach their target sites within the skin.

Formulation Guidelines

BIO-Placenta is a water-based liquid that integrates easily into serums, creams, and lotions. To preserve growth factor integrity, add during the cool-down phase below 40°C (104°F). It performs best within pH 4.5–7.0 and is compatible with common actives such as hyaluronic acid, niacinamide, antioxidants, and botanical extracts. For comprehensive anti-aging products, pair with antioxidants and barrier-repair lipids. Recommended usage is 2%–3% for daily moisturizers and 4%–5% for intensive serums, ampoules, and targeted treatments.

Key Formulation Benefits

Clinically Proven Efficacy: Demonstrates significant improvements in wrinkle reduction, hydration, and elasticity within 2–4 weeks.
Multi-Functional Anti-Aging: Addresses wrinkles, loss of firmness, and dehydration with a single, comprehensive active.
Biomimetic Technology: Utilizes synthesized growth factors identical to human counterparts for high compatibility and performance.
Enhanced Penetration: Liposomal (lecithin-based) delivery optimizes skin absorption and active stability.
Excellent Stability: Pre-solubilized, preserved liquid format simplifies formulation and ensures consistent results.
Ethical & Safe: Fermentation-derived, vegan, and cruelty-free alternative to animal- or human-derived placental materials.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Collagen Boosting, Deep Hydration, Firming & Lifting, Moisturizing & Hydration, Wrinkle Reduction
INCI Name	Water, Lecithin, Acetyl glutamine, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-11, Bacillus/ Folic Acid Ferment Extract, Sodium Hyaluronate, Caprylyl Glycol, Butylene Glycol, 1,2-Hexanediol
Usage Rate	2%-5%
Active Type	Biotech/Fermentation Actives, Fermented Ingredients, Growth Factors, Peptides
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About BIO-Placenta

No. BIO-Placenta is a completely synthetic and ethical ingredient. The growth factors are created through microbial fermentation and are biomimetic—structurally identical to human growth factors but not derived from human or animal tissues.

The recommended concentration is 2%–5%. Use 2%–3% for daily anti-aging moisturizers and up to 5% for high-potency serums, ampoules, and targeted treatments.

It mimics the rich composition of growth factors, vitamins, and amino acids found in mammalian placenta—key elements for cell growth and regeneration—using safe, controlled, and ethical biotechnology.

Yes. It pairs well with hyaluronic acid, niacinamide, and antioxidants. When formulating with potent actives like L-Ascorbic Acid or Retinol, ensure the final pH remains within 4.5–7.0 and conduct stability testing.

BIO-Placenta stimulates cellular communication and regeneration. The five growth factors signal skin cells (e.g., fibroblasts) to increase collagen and elastin production, accelerate turnover, and repair damage for visibly younger, healthier skin.

Maintain the final formulation pH between 4.5 and 7.0 to ensure growth factor stability and efficacy.

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