Aqua-ProVita D3

Bioactive Pro-Vitamin D3 for Advanced Skin Barrier Repair and Defense

INCI Name: Glycerin, Methyl Cyclodextrin, Water, 7-Dehydrocholesterol

Aqua-ProVita D3 is an advanced, water-soluble cosmetic active that delivers stabilized 7-Dehydrocholesterol (Pro-Vitamin D3) to the skin. Utilizing a unique cyclodextrin encapsulation technology, it enhances the bioavailability of this essential precursor, allowing the skin to naturally synthesize Vitamin D3 when exposed to UV light. This mechanism strengthens the skin’s lipid barrier, reduces irritation, and improves overall skin health, making it ideal for restorative, protective, and anti-aging formulations.

Solubility Notes:

Water-soluble. Add to the water phase or during the cool-down phase of formulation below 40°C.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Barrier Repair Creams

Reinforces the skin's natural lipid barrier to reduce transepidermal water loss (TEWL) and improve resilience against environmental stressors.
Anti-Aging Serums

Supports healthy cellular differentiation and epidermal renewal to improve skin texture and reduce visible signs of aging.
Soothing & Calming Lotions

Helps reduce irritation and redness by modulating the skin's natural immune response for a calmer, more balanced complexion.
Daily Moisturizers

Delivers essential building blocks for skin health, promoting deep hydration and maintaining a strong, functional barrier.
Sun Care & After-Sun Products

Supports the skin’s ability to manage UV exposure by supplying Pro-Vitamin D3, aiding natural defense and post-exposure repair mechanisms.
Scalp Health Treatments

Nourishes the scalp to support a healthy barrier, reducing irritation and creating an optimal environment for hair follicles.

Performance & Formulation Insights for Aqua-ProVita D3

How Pro-Vitamin D3 Works

Aqua-ProVita D3 delivers 7-Dehydrocholesterol (7-DHC), the natural precursor to Vitamin D3 found in the skin. In the epidermis, UVB radiation converts 7-DHC into Vitamin D3, a critical signaling molecule that supports keratinocyte differentiation, lipid barrier formation, and innate immunity. Because 7-DHC is inherently unstable and oil-soluble, it is challenging to formulate in conventional systems. Aqua-ProVita D3 resolves this with a Methyl Cyclodextrin encapsulation that shields 7-DHC from degradation and renders it water-soluble for easy incorporation. This delivery system creates a stable, bioavailable reservoir of 7-DHC that the skin can utilize to produce Vitamin D3 as needed, enhancing its natural defense, repair, and regeneration processes.

Formulation Guidelines

Aqua-ProVita D3 is a user-friendly, viscous liquid designed for the water phase of formulations. For optimal stability, add during the cool-down phase below 40°C (104°F). It is stable in a pH range of 5.0–7.0 and is readily compatible with serums, toners, emulsions, gels, and gentle cleansers without the need for complex solubilizers.

Key Formulation Benefits

Enhanced Barrier Function: Strengthens the skin’s lipid barrier to improve moisture retention and protect against external irritants.
Stabilized & Bioavailable: Cyclodextrin encapsulation protects highly unstable 7-Dehydrocholesterol, ensuring potent delivery and bioavailability.
Reduces Skin Irritation: Helps modulate the skin’s inflammatory response, visibly reducing redness and sensitivity.
Supports UV Resistance: Provides a topical pool of Pro-Vitamin D3 to help fortify the skin’s natural defenses against UV-induced stress.
Easy to Formulate: Water-soluble liquid integrates seamlessly into clear serums, gels, and emulsions.
Anti-Microbial Properties: Supports the skin’s natural antimicrobial peptide production for a balanced microbiome.

Heading #1
Benefits	Barrier Repair, Moisturizing & Hydration, Soothing & Anti-Inflammatory, UV Damage Repair, UV Protection & Defense
INCI Name	Glycerin, Methyl Cyclodextrin, Water, 7-Dehydrocholesterol
Usage Rate	1%-4%
Active Type	Biotech/Fermentation Actives, Vitamin D, Vitamins & Derivatives
Solubility	Water-Soluble
Application Area	Body, Face, Hair, Scalp
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About Aqua-ProVita D3

The recommended usage level is 1% to 4%, depending on desired efficacy and application, such as daily care or intensive treatment.

Aqua-ProVita D3 provides the precursor, 7-Dehydrocholesterol, which the skin uses to synthesize Vitamin D3 upon UVB exposure. It supports localized skin functions rather than systemic Vitamin D levels.

Methyl Cyclodextrin encapsulates 7-Dehydrocholesterol to stabilize the molecule, make it water-soluble, and enhance delivery into the epidermis.

Yes. It is suitable for daily sun care and after-sun formulations, helping the skin cope with UV-induced stress and supporting natural repair processes.

It is typically produced via fermentation or synthetic methods, making it suitable for vegan and cruelty-free formulations.

Maintain a final formulation pH between 5.0 and 7.0 for maximum stability and performance.

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