Performance & Formulation Insights for AccessWHITE TXA
How Tranexamic Acid Works
AccessWHITE TXA functions by inhibiting UV-induced plasmin activity in the skin. Plasmin, an enzyme present in the epidermis, can accelerate melanin production by increasing tyrosinase activity and stimulating the transfer of melanosomes to keratinocytes. Tranexamic Acid blocks the conversion of plasminogen to plasmin, interrupting this melanogenesis cascade. This mechanism not only reduces the formation of new pigment but also confers anti-inflammatory benefits, helping to calm the skin and reduce the redness and vascularity often associated with conditions like melasma and PIH.
Formulation Guidelines
AccessWHITE TXA is a water-soluble powder that should be incorporated into the water phase of your formulation. It is stable across a broad pH range (3.0–8.0); for optimal skin compatibility and efficacy, target a final pH of 5.0–7.0. The recommended usage rate is 2–5%. It can be combined with complementary brightening agents such as Niacinamide, Vitamin C derivatives, Kojic Acid, and Arbutin for a synergistic effect. Avoid formulating with strong acids without careful pH management to ensure stability and performance of all actives.
Key Formulation Benefits
- Clinically Proven Efficacy: Widely studied for reducing melasma, hyperpigmentation, and post-inflammatory redness.
- Multi-Pathway Action: Addresses both pigmentary and vascular (redness) components of uneven tone.
- Excellent Safety Profile: Gentle and suitable for all skin types, including sensitive and acne-prone skin.
- Synergistic Potential: Pairs well with Niacinamide, Vitamin C derivatives, Kojic Acid, and Arbutin for comprehensive brightening.
- Versatile Application: Easy to formulate into serums, creams, lotions, and targeted spot treatments.
- Post-Treatment Specialist: Recommended after aesthetic procedures (e.g., lasers, peels) to help prevent post-inflammatory pigmentation.