AccessWHITE Glabridin-90

Q: What is the recommended usage rate for AccessWHITE Glabridin-90?

The recommended usage rate is typically between 0.05% and 0.2% in a finished formulation due to its high purity and potency.

Q: How does Glabridin-90 differ from standard licorice root extract?

AccessWHITE Glabridin-90 is a highly purified isolate containing at least 90% Glabridin, the most active brightening molecule in licorice. Standard licorice extracts contain a mixture of compounds with much lower Glabridin content, resulting in significantly lower brightening potency.

Q: Is Glabridin soluble in water?

No. Glabridin is oil-soluble and insoluble in water. Pre-dissolve in a suitable solvent (e.g., glycol, cosmetic ester, or ethanol) and add to the oil phase or during the cool-down phase of an emulsion.

Q: Can Glabridin-90 be used with Vitamin C or Niacinamide?

Yes. Glabridin works synergistically with other brighteners and is compatible with Niacinamide and stable Vitamin C derivatives, enabling a multi-pathway approach to hyperpigmentation.

Q: What is the optimal pH range for formulations containing Glabridin?

Maintain formulations within pH 4.5 to 6.5 to ensure stability and bioavailability of the active.

Q: Is special packaging required for products with Glabridin?

Yes. Because Glabridin can be light-sensitive, opaque or UV-protective packaging is strongly recommended to preserve long-term stability and efficacy.

High-Purity Botanical Brightener for Targeted Hyperpigmentation Control

INCI Name: Glabridin

AccessWHITE Glabridin-90 is a high-potency, purified active powder containing 90% Glabridin, derived from licorice root (Glycyrrhiza glabra). As one of the most effective natural brighteners, it acts as a powerful tyrosinase inhibitor to prevent melanin synthesis and correct hyperpigmentation. Strong antioxidant and anti-inflammatory properties further promote an even, radiant tone, making it ideal for advanced brightening serums and dark spot correctors.

Solubility Notes:

Oil-soluble and insoluble in water. Soluble in glycols (e.g., propylene glycol, butylene glycol), cosmetic esters, and ethanol. Pre-dissolve (≈1:10 or higher) and add to the oil phase or during cool-down (<45°C / 113°F).

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Dark Spot Correctors & Treatments

Delivers a highly concentrated dose to specific areas of hyperpigmentation for targeted and visible reduction of age spots, sun spots, and post-inflammatory marks.
Brightening Serums

Formulates into lightweight, high-performance serums to promote an overall even skin tone and enhance luminosity across the entire face.
Even-Tone Moisturizers & Creams

Incorporates into daily-use creams to continuously manage pigmentation and maintain a clear, uniform complexion.
Anti-Aging & Brightening Complexes

Combines powerful antioxidant and anti-inflammatory benefits with brightening action in multi-functional anti-aging formulations.
Sun Care & After-Sun Products

Helps prevent the formation of UV-induced pigmentation and soothes skin when included in protective sun care and reparative after-sun formulations.
Brightening Cosmetic Foundations & Concealers

Adds active, long-term skin tone correcting benefits to color cosmetic products for treatment and coverage in one.

Performance & Formulation Insights for AccessWHITE Glabridin-90

Mechanism of Action: How Glabridin Brightens Skin

AccessWHITE Glabridin-90 achieves its potent brightening effects primarily by inhibiting tyrosinase, the rate-limiting enzyme in melanin production. Glabridin’s molecular structure enables it to bind to the active site of tyrosinase, competitively inhibiting its activity without affecting cell proliferation. This blocks the conversion of tyrosine into melanin precursors, effectively preventing pigment formation before it starts. Beyond tyrosinase inhibition, Glabridin is a strong antioxidant that scavenges free radicals known to trigger melanogenesis and contribute to cellular damage. It also displays significant anti-inflammatory properties, helping to calm irritated skin and reduce the risk of post-inflammatory hyperpigmentation (PIH).

Formulation Guidelines for Optimal Performance

AccessWHITE Glabridin-90 is a high-purity (90%), oil-soluble powder with exceptional potency, effective at very low use levels of 0.05% to 0.2%. For best results, pre-dissolve the powder in a suitable solvent (e.g., butylene glycol, pentylene glycol, cosmetic esters, or ethanol) at a ratio of 1:10 or higher before incorporation. Add the solubilized Glabridin during the cool-down phase at temperatures below 45°C (113°F) to preserve activity. The active is stable within a cosmetic pH range of 4.5–6.5 and is compatible with complementary brighteners (Niacinamide, Arbutin, Vitamin C derivatives) as well as antioxidants and peptides. Because Glabridin can be light-sensitive, use opaque or UV-protective packaging to maintain long-term stability and efficacy.

Key Formulation Benefits

High-Potency Brightening: Delivers significant depigmenting effects at very low concentrations for targeted results.
Clinically Supported: One of the most researched botanical brighteners with demonstrated efficacy in reducing hyperpigmentation.
Multi-Pathway Action: Combines tyrosinase inhibition with antioxidant and anti-inflammatory activity for comprehensive tone correction.
Botanical & Consumer-Friendly: Derived from licorice root (Glycyrrhiza glabra), appealing to consumers seeking effective, plant-based solutions.
Gentle & Non-Cytotoxic: Known for a favorable safety profile suitable for a wide range of skin types.
Formulation Versatility: Suitable for emulsions, anhydrous systems, and oil-based serums across skincare and hybrid color formats.

Heading #1
Benefits	Antioxidants, Brightening & Skin Lightening, Dark Spot Reduction, Soothing & Anti-Inflammatory, Tyrosinase Inhibition
INCI Name	Glabridin
Usage Rate	0.05%-0.2%
Active Type	Botanical Extracts & Phytoactives, Other Botanical Extracts
Solubility	Oil-Soluble
Application Area	Body, Face
Physical Form	Powder
Certifications	Cruelty-Free, Natural (ISO 16128), Vegan

Frequently Asked Questions About AccessWHITE Glabridin-90

The recommended usage rate is typically between 0.05% and 0.2% in a finished formulation due to its high purity and potency.

AccessWHITE Glabridin-90 is a highly purified isolate containing at least 90% Glabridin, the most active brightening molecule in licorice. Standard licorice extracts contain a mixture of compounds with much lower Glabridin content, resulting in significantly lower brightening potency.

No. Glabridin is oil-soluble and insoluble in water. Pre-dissolve in a suitable solvent (e.g., glycol, cosmetic ester, or ethanol) and add to the oil phase or during the cool-down phase of an emulsion.

Yes. Glabridin works synergistically with other brighteners and is compatible with Niacinamide and stable Vitamin C derivatives, enabling a multi-pathway approach to hyperpigmentation.

Maintain formulations within pH 4.5 to 6.5 to ensure stability and bioavailability of the active.

Yes. Because Glabridin can be light-sensitive, opaque or UV-protective packaging is strongly recommended to preserve long-term stability and efficacy.

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