Performance & Formulation Insights for AccessWHITE Glabridin-40
How Glabridin Brightens and Protects Skin
AccessWHITE Glabridin-40 delivers potent skin-brightening by directly inhibiting tyrosinase, the rate-limiting enzyme in melanin synthesis. By interrupting this key step in melanogenesis, Glabridin helps prevent excess pigment formation, visibly reducing dark spots and promoting a more even tone. In addition to its depigmenting effect, Glabridin exhibits strong antioxidant activity with SOD-like behavior, scavenging free radicals generated by UV exposure and pollution to mitigate oxidative stress. Its inherent anti-inflammatory action further helps soothe the skin and reduce the look of redness, making it suitable for sensitive skin brightening routines.
Formulation Guidelines for Optimal Performance
AccessWHITE Glabridin-40 is a fine, yellowish-brown powder that is oil-soluble and insoluble in water. For proper incorporation, pre-dissolve in a suitable solvent such as butylene glycol, propylene glycol, or ethanol at approximately a 1:10 ratio (Glabridin to solvent). Gently heat the mixture to 40–60°C to ensure complete dissolution, then add the solution to the oil phase of your formulation. Due to its high 40% Glabridin content, effective use levels are very low (0.02–0.1%). It is stable in typical cosmetic pH conditions (pH 4.0–7.0). For best results, include complementary antioxidants and chelating agents to enhance stability and overall performance.
Key Formulation Benefits
- Potent Tyrosinase Inhibition: Effectively targets the melanin pathway to reduce hyperpigmentation and promote a brighter, more uniform complexion.
- High Purity, Low Use Level: The 40% Glabridin standardization enables impactful results at just 0.02–0.1%.
- Dual Antioxidant & Anti-Inflammatory: Provides SOD-like antioxidant activity while helping to calm visible redness and irritation.
- Clinically Supported: Glabridin is a well-researched licorice-derived active with documented brightening and antioxidant benefits.
- Excellent Synergy: Pairs well with Vitamin C derivatives, Niacinamide, and Arbutin for multi-pathway brightening strategies.
- Plant-Derived: A naturally sourced active that aligns with consumer demand for effective botanical ingredients.