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AccessPEP TTP-30

Advanced Brightening Peptide for Even Skin Tone and Dark Spot Reduction

INCI Name: Tetrapeptide-30

AccessPEP TTP-30 is a biomimetic peptide engineered to brighten the skin and correct hyperpigmentation. Featuring Tetrapeptide-30, this active inhibits tyrosinase—key to melanin production—and helps reduce melanin transfer to skin cells. Its targeted action visibly minimizes dark spots, sun spots, and post-inflammatory hyperpigmentation, promoting a more uniform and radiant complexion.

Solubility Notes:

Water-soluble; add to the water phase or during the cool-down phase of formulation (<40°C).

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Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

  • Brightening & Dark Spot Serums
    Delivers a concentrated dose of peptide to visibly fade dark spots and help prevent new ones from forming in targeted, lightweight serums.
  • Even Skin Tone Moisturizers
    Integrates seamlessly into daily-use creams and lotions to promote a consistently even, luminous complexion over time.
  • Spot-Correcting Treatments
    Provides potent, localized action in spot correctors to diminish the appearance of age spots, sun spots, and post-acne marks.
  • Brightening Foundations & Concealers
    Incorporates into color cosmetic formulas like foundations and concealers to deliver long-term brightening benefits alongside instant coverage.
  • Radiance-Boosting Face Masks
    Enhances the efficacy of sheet masks and wash-off treatments, offering an intensive brightening boost for dull, uneven skin.
  • Sun Care & After-Sun Products
    Helps manage and mitigate pigmentary effects of UV exposure when included in daily sunscreens or after-sun repair lotions.

Performance & Formulation Insights for AccessPEP TTP-30

How Tetrapeptide-30 Works

AccessPEP TTP-30 delivers a multi-pathway approach to visible skin brightening. Its primary action is the downregulation of tyrosinase, the rate-limiting enzyme that initiates melanin synthesis. By reducing tyrosinase activity, Tetrapeptide-30 helps decrease overall melanin formation. In addition, it helps modulate melanocyte activation triggered by UV exposure and inflammation, and reduces the transfer of melanin to surrounding skin cells. This comprehensive mechanism fades existing dark spots and helps prevent the formation of new hyperpigmentation for a clearer, more even skin tone.

Formulation Guidelines

AccessPEP TTP-30 is water-soluble and integrates easily into the aqueous phase of emulsions, serums, and toners. Add during the cool-down phase at temperatures below 40°C (104°F) to preserve peptide integrity. The ideal final pH is 4.5–6.5. It is compatible with complementary brightening actives such as Niacinamide and Vitamin C derivatives, enabling synergistic, multi-active formulas. Pairing with exfoliants (e.g., AHAs) or retinoids can further enhance visible brightening by accelerating turnover of pigmented surface cells.

Key Formulation Benefits

  • Clinically Proven Efficacy: Supported by in-vivo and in-vitro data demonstrating reductions in hyperpigmentation and improved tone uniformity.
  • Targeted Dark Spot Reduction: Addresses age spots, sun spots, and post-inflammatory hyperpigmentation with a focused mechanism.
  • Promotes Overall Radiance: Helps normalize melanin distribution for a brighter, more luminous complexion.
  • Excellent Safety Profile: Gentle yet effective alternative to harsher brighteners, suitable for a wide range of skin types.
  • Formulation Versatility: Water-soluble and stable within skin-friendly pH; suitable for serums, creams, masks, and color cosmetics.
  • Prevents Future Pigmentation: Helps interrupt signals that trigger melanin synthesis to proactively maintain an even tone.
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Benefits
Brightening & Skin Lightening, Dark Spot Reduction, Even Skin Tone, Tyrosinase Inhibition
INCI Name
Tetrapeptide-30
Usage Rate
0.5%-5%
Active Type
Brightening Peptides, Peptides
Solubility
Water-Soluble
Application Area
Body, Face
Physical Form
Liquid/Solution
Certifications
Cruelty-Free, Vegan

Frequently Asked Questions About AccessPEP TTP-30

The recommended usage level is 0.5% to 5.0%, depending on desired efficacy and product format. For intensive spot treatments, use the higher end of the range.
Tetrapeptide-30 is a biomimetic peptide that targets signaling pathways driving melanin production. While Vitamin C provides antioxidant support and Arbutin inhibits tyrosinase, Tetrapeptide-30 offers a targeted, cell-communicating approach that helps prevent hyperpigmentation at the source, with strong stability and low irritation potential.
Yes. It can be combined with AHAs and retinoids for complementary effects: exfoliants help remove pigmented surface cells while the peptide works to inhibit new melanin production. Maintain final pH between 4.5 and 6.5 for peptide stability.
For maximum stability and performance, formulate within a pH range of 4.5–6.5.
Visible improvements in tone evenness are typically observed within 4–8 weeks of consistent twice-daily use, with more significant dark spot reduction by 8–12 weeks.
Yes. Tetrapeptide-30 is known for excellent skin tolerance and is considered a gentle brightening option suitable for sensitive skin types.

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AccessPEP TTP-30

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