AccessPEP TPP-30S

High-Performance Brightening Peptide for Even Skin Tone and Hyperpigmentation

INCI Name: Glycerin, Tetrapeptide-30

AccessPEP TPP-30S is an advanced brightening peptide featuring Tetrapeptide-30 in a glycerin base for easy formulation. It is expertly designed to reduce hyperpigmentation, diminish dark spots, and promote a more even, luminous skin tone. By inhibiting key pathways in melanin production and transfer, this peptide offers a targeted approach to correcting discoloration and is ideal for brightening serums, spot treatments, and daily moisturizers.

Solubility Notes:

Water-soluble; add to the water phase during the cool-down process below 40°C (104°F).

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Brightening & Dark Spot Serums

Delivers a concentrated dose of peptide to visibly reduce the appearance of sun spots, age spots, and post-acne marks.
Even Tone Face Creams

Integrates seamlessly into daily moisturizers to promote a uniform complexion and prevent future discoloration.
Targeted Spot Correctors

Perfect for intensive spot treatments designed to be applied directly to areas of hyperpigmentation for focused results.
Brightening Eye Creams

Gently addresses periorbital hyperpigmentation (dark circles) to create a brighter, more rested appearance.
Radiance-Boosting Toners & Essences

Enhances skin clarity and luminosity in lightweight, preparatory formulations that can be layered with other products.
Body Lightening Lotions

Effectively treats areas of hyperpigmentation on the body, such as the hands, chest, and shoulders.

Performance & Formulation Insights for AccessPEP TPP-30S

How Tetrapeptide-30 Brightens Skin

AccessPEP TPP-30S leverages Tetrapeptide-30, a biomimetic peptide that targets multiple steps in the pigmentation pathway. Its primary mechanism involves down-regulating tyrosinase, the key enzyme required for melanin synthesis. In parallel, it helps interrupt melanosome transfer from melanocytes to keratinocytes by inhibiting the PAR-2 pathway, reducing the amount of pigment that reaches the skin surface. This dual-action approach both decreases new pigment formation and limits the visibility of existing pigment. Additionally, Tetrapeptide-30 exhibits anti-inflammatory activity, helping to minimize post-inflammatory hyperpigmentation (PIH) associated with acne and irritation.

Formulation Guidelines for Optimal Performance

AccessPEP TPP-30S is a glycerin-based, water-soluble solution that integrates easily into the water phase of serums, lotions, and creams. To preserve peptide integrity, add during the cool-down phase at temperatures below 40°C (104°F). It performs well within a pH range of 4.0 to 7.0. For enhanced brightening and anti-aging results, combine synergistically with Niacinamide, Vitamin C derivatives (e.g., Sodium Ascorbyl Phosphate), and hydrating polymers like Hyaluronic Acid. Recommended usage levels are 1% to 4%, with higher levels suited for targeted treatments and spot correctors.

Key Formulation Benefits

Clinically Proven Efficacy: Reduces hyperchromatic spots, brightens skin, and promotes a more uniform skin tone.
Targeted Hyperpigmentation Control: Visibly diminishes sun spots, age spots, and post-inflammatory hyperpigmentation.
Anti-Inflammatory Action: Helps calm irritated skin and reduce redness and discoloration associated with acne lesions.
Excellent Formulation Compatibility: Plays well with common brightening and anti-aging actives for multi-pathway solutions.
Easy to Incorporate: Clear, water-soluble liquid ensures simple, homogeneous integration into serums, creams, and lotions.
High Safety Profile: Gentle yet effective alternative to harsher lightening agents; suitable for a range of skin types.

Heading #1
Benefits	Brightening & Skin Lightening, Dark Spot Reduction, Even Skin Tone, Soothing & Anti-Inflammatory
INCI Name	Glycerin, Tetrapeptide-30
Usage Rate	1%-4%
Active Type	Brightening Peptides, Peptides
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessPEP TPP-30S

The recommended usage rate is between 1% and 4%. Use lower concentrations for daily maintenance products and higher concentrations for targeted treatment serums and spot correctors.

It uses a dual mechanism: it down-regulates tyrosinase to reduce melanin synthesis and inhibits melanosome transfer via the PAR-2 pathway to limit pigment reaching the skin surface. Its anti-inflammatory effect also helps reduce post-acne marks.

Yes. It is highly compatible and works synergistically with Niacinamide and stable Vitamin C derivatives (e.g., Sodium Ascorbyl Phosphate) for a comprehensive, multi-pathway approach to hyperpigmentation.

This peptide is stable and effective in a pH range of 4.0 to 7.0, suitable for most skin care systems.

Yes. Its anti-inflammatory properties make it effective at reducing the appearance of dark spots and redness left by acne lesions.

With consistent use in a well-formulated product, visible improvements in tone evenness and dark spots may be seen within 4 to 8 weeks.

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