AccessPEP PTP-1

High-Performance Collagen-Boosting Peptide for Skin Firmness and Wrinkle Reduction

INCI Name: Palmitoyl Tripeptide-1

AccessPEP PTP-1 is a powerful biomimetic peptide featuring Palmitoyl Tripeptide-1, a matrikine signal peptide that supports the skin’s natural regeneration processes. By mimicking a fragment of Type I collagen, it encourages fibroblasts to synthesize new collagen, elastin, and glycosaminoglycans, rebuilding the dermal matrix. The result is improved firmness and elasticity with visible reductions in fine lines, wrinkles, and surface roughness.

Solubility Notes:

Water-soluble. Add to the water phase of your formulation or during the cool-down phase below 40°C.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Firming & Lifting Serums

Delivers concentrated peptides to boost collagen production for a visibly firmer, lifted, more youthful skin contour.
Anti-Wrinkle Face Creams

Integrates into daily moisturizers to progressively reduce wrinkles and improve overall texture and smoothness.
Eye Contour Creams

Targets fine lines and loss of firmness in the delicate eye area for a revitalized, smoother appearance.
Barrier Repair & Anti-Aging Moisturizers

Strengthens dermal structure in advanced moisturizers, enhancing resilience and hydration.
Body Firming Lotions

Improves skin tonicity and elasticity in body care to address areas prone to sagging or texture irregularities.
Collagen-Boosting Treatments

Key active for targeted treatments and masks designed to promote dermal density and structural integrity.

Performance & Formulation Insights for AccessPEP PTP-1

How Palmitoyl Tripeptide-1 Works

AccessPEP PTP-1 is a biomimetic “matrikine” signal peptide that communicates with skin cells to trigger renewal. Palmitoyl Tripeptide-1 (Pal-GHK) mimics a fragment of Type I collagen. When collagen degrades, similar peptide fragments signal fibroblasts to synthesize new structural proteins. By supplying Palmitoyl Tripeptide-1 topically, we encourage fibroblasts to increase production of collagen, elastin, and glycosaminoglycans (including hyaluronic acid), rebuilding the dermal matrix. This remodeling leads to improved firmness, elasticity, and visible reductions in wrinkle depth and surface roughness.

Formulation Guidelines

AccessPEP PTP-1 integrates easily into aqueous phases and emulsions. Add to the water phase or during cool-down below 40°C (104°F) to preserve peptide integrity. It performs reliably within pH 4.5–7.0 and pairs well with complementary actives, including Palmitoyl Tetrapeptide-7, hyaluronic acid, vitamin C derivatives, and antioxidants for comprehensive age-defense systems. Recommended usage: 1–5%.

Key Formulation Benefits

Clinically Proven Efficacy: Increases collagen and glycosaminoglycan synthesis for measurable improvements in firmness and wrinkle reduction.
Dermal Restructuring: Rebuilds the skin’s support matrix to enhance density, elasticity, and smoothness.
Excellent Stability: Robust performance across a practical pH range (4.5–7.0) in diverse cosmetic bases.
Enhanced Penetration: The palmitoyl moiety increases lipophilicity to support effective delivery to target cells.
Synergistic Power: Works synergistically with Palmitoyl Tetrapeptide-7 (e.g., Matrixyl 3000 concepts) and other anti-aging actives.
High Compatibility: Formulates seamlessly alongside HA, vitamin C derivatives, antioxidants, and modern emulsifier systems.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Collagen Boosting, Firming & Lifting, Wrinkle Reduction
INCI Name	Palmitoyl Tripeptide-1
Usage Rate	1%-5%
Active Type	Anti-Wrinkle Peptides, Peptides
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessPEP PTP-1

The recommended usage rate is 1–5%. For general anti-aging, 1–3% is effective; up to 5% can be used for intensive firming and wrinkle-repair treatments.

It is a signal peptide that mimics a collagen fragment to stimulate new collagen synthesis, unlike neurotransmitter-inhibiting peptides that soften expression lines or carrier peptides that deliver trace elements.

The peptide performs best at a final pH between 4.5 and 7.0.

Yes, but strategy matters. Formulate peptides above pH 4.5. With low-pH AHA systems or retinol, consider protective delivery systems or alternate application times to maintain efficacy.

It is a synthetic, nature-identical peptide produced to match a skin-native fragment; it is not animal-derived.

Visible improvements in texture and wrinkle depth are commonly observed within 4–8 weeks of consistent twice-daily use.

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