AccessPEP PT-5

High-Performance Collagen-Boosting Peptide for Wrinkle Reduction and Skin Firming

INCI Name: Aqua, Glycerin, Palmitoyl Tripeptide-5, Phenoxyethanol, Ethylhexylglycerin

AccessPEP PT-5 is a potent cosmetic active featuring Palmitoyl Tripeptide-5, a biomimetic peptide engineered to stimulate the skin’s natural collagen production. By activating the key growth factor TGF-β, it significantly improves skin texture, reduces the appearance of fine lines and deep wrinkles, and enhances overall firmness. This easy-to-use, water-soluble solution is ideal for formulators creating advanced anti-aging creams, firming serums, and hydrating treatments.

Solubility Notes:

Water-soluble, add to the water phase or during the cool-down phase below 40°C.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Anti-Aging & Firming Serums

Delivers a concentrated dose of peptide to visibly reduce wrinkle depth and improve skin elasticity in lightweight, targeted formulations.
Face Creams & Moisturizers

Integrates seamlessly into daily-use creams to provide continuous collagen support, improving skin texture and hydration.
Eye Creams & Treatments

Safely and effectively targets fine lines and crow's feet in the delicate eye area, helping to firm and smooth the skin.
Body Firming Lotions

Improves skin tone and elasticity on the body, particularly in formulations targeting areas like the neck, décolleté, and hands.
Night Repair Products

Works overnight in restorative creams and masks to support the skin's natural repair cycle and boost collagen synthesis.
Skin Plumping Treatments

Helps to rebuild the dermal matrix, resulting in a plumper, more youthful appearance in targeted treatment products.

Performance & Formulation Insights for AccessPEP PT-5

How Palmitoyl Tripeptide-5 Works

AccessPEP PT-5 harnesses the power of Palmitoyl Tripeptide-5, a small, biomimetic peptide that mimics the skin’s own signaling to stimulate collagen production. Its primary action is the activation of Transforming Growth Factor-beta (TGF-β), a key regulator that signals fibroblasts to synthesize new collagen, helping rebuild the dermal matrix from within. In parallel, it helps safeguard existing collagen by attenuating Matrix Metalloproteinases (MMPs), the enzymes responsible for collagen breakdown. This dual strategy—boosting neocollagenesis while protecting existing structural proteins—visibly reduces fine lines and wrinkles and improves firmness, elasticity, and overall skin texture.

Formulation Guidelines

AccessPEP PT-5 is a user-friendly, water-soluble liquid designed for straightforward incorporation into serums, gels, and emulsions. Add to the water phase or during the cool-down phase below 40°C (104°F) to preserve peptide integrity. It is stable across a pH of 4.0–7.0, offering broad compatibility with standard skincare systems. Recommended use level is 1–5%. It pairs synergistically with Hyaluronic Acid, Niacinamide, Vitamin C derivatives, and complementary peptides for multi-pathway anti-aging performance.

Key Formulation Benefits

Clinically Proven Efficacy: Visibly reduces the appearance of wrinkles and refines overall skin texture.
Dual-Action Wrinkle Repair: Stimulates Type I & Type III collagen synthesis while helping protect against enzymatic degradation (MMPs).
Excellent Stability: Performs reliably within a wide, skin-friendly pH range (4.0–7.0).
Easy to Formulate: Clear, water-soluble solution that incorporates without heating in serums, gels, and emulsions.
High Compatibility: Works seamlessly alongside common anti-aging actives for synergistic results.
Superior Skin Penetration: Palmitoyl modification enhances lipophilicity, supporting effective delivery to the dermal layer.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Collagen Boosting, Firming & Lifting, Wrinkle Reduction
INCI Name	Aqua, Glycerin, Palmitoyl Tripeptide-5, Phenoxyethanol, Ethylhexylglycerin
Usage Rate	1%-5%
Active Type	Anti-Wrinkle Peptides, Peptides
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessPEP PT-5

The recommended usage rate is 1–5%. Use 1–3% for general anti-aging products and 3–5% for intensive firming and wrinkle-repair treatments.

Palmitoyl Tripeptide-5 primarily activates TGF-β to boost collagen synthesis. Unlike neuromodulating peptides (e.g., Acetyl Hexapeptide-8) or mineral-delivery peptides (e.g., copper peptides), PT-5 directly signals skin to rebuild its structural foundation.

Yes. Add during the cool-down phase below 40°C (104°F) to preserve peptide integrity and efficacy.

AccessPEP PT-5 is stable and effective between pH 4.0 and 7.0.

Yes. When formulating with low-pH ingredients like AHAs, ensure the final pH remains within 4.0–7.0. It can also be combined effectively with Retinol in anti-aging regimens.

Reduced wrinkle depth, improved firmness and elasticity, and a smoother, more refined skin texture.

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