AccessPEP NON-1 sol.

Advanced Brightening Peptide for Even Skin Tone and Dark Spot Reduction

INCI Name: Aqua, Glycerin, Nonapeptide-1, Phenoxyethanol, Ethylhexylglycerin

AccessPEP NON-1 sol. is a high-performance cosmetic active featuring Nonapeptide-1, a biomimetic peptide that helps correct and prevent unwanted pigmentation. By antagonizing α-MSH at the MC1R receptor, it interrupts the initial signal for melanin synthesis, promoting a brighter, more even complexion and reducing the appearance of dark spots. This water-soluble solution integrates seamlessly into advanced brightening serums, spot correctors, and tone-evening treatments.

Solubility Notes:

Water-soluble. Add to the water or cool-down phase at or below 40 °C. Formulate within pH 4.5–7.0 for optimal stability.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Brightening & Dark Spot Serums

Concentrated delivery of Nonapeptide-1 to target hyperpigmentation and help prevent new dark spots.
Even Skin Tone Moisturizers

Integrates into daily creams and lotions to support a consistently bright, uniform complexion.
Targeted Spot Treatments

Provides intensive action to diminish the look of age spots, sun spots, and post-inflammatory hyperpigmentation.
Anti-Aging & Brightening Creams

Addresses uneven tone alongside visible signs of aging for comprehensive complexion improvement.
Brightening Sheet Masks & Peels

Boosts wash-off or leave-on treatments for immediate radiance and tone-evening support.
Cosmetic Base & Foundation Primers

Incorporates into color cosmetics to deliver long-term brightening benefits alongside instant coverage.

Performance & Formulation Insights for AccessPEP NON-1 sol.

How Nonapeptide-1 Achieves a Brighter Complexion

AccessPEP NON-1 sol. features Nonapeptide-1, a biomimetic peptide that targets the earliest step of melanogenesis. It acts as a competitive antagonist to α-Melanocyte Stimulating Hormone (α-MSH) by binding to the MC1R receptor on melanocytes without activating it. By blocking α-MSH from initiating the signaling cascade, it helps inhibit tyrosinase activity and reduce melanin synthesis. The result is a visibly brighter, more even skin tone and a reduction in the appearance of dark spots caused by UV exposure, aging, or post-inflammatory hyperpigmentation.

Formulation Guidelines & Technical Advantages

Supplied as a water-soluble liquid, AccessPEP NON-1 sol. is easy to incorporate into the water phase or cool-down phase of serums, emulsions, and gel systems. For optimal stability and performance, formulate within a pH range of 4.5–7.0 and add at or below 40 °C. It is compatible with a wide range of cosmetic actives, including Vitamin C derivatives, Niacinamide, and Alpha-Arbutin for multi-pathway brightening. It also pairs well with exfoliants such as AHAs, which can enhance penetration and help accelerate visible tone-evening results.

Key Formulation Benefits

Prevents Hyperpigmentation: Acts on the initial hormonal trigger of melanogenesis to help prevent new dark spots.
Reduces Existing Discoloration: Gradually improves the look of sun spots, age spots, and PIH for a more uniform complexion.
Promotes Even Skin Tone: Delivers global brightening and enhanced radiance.
Formulation Friendly: Water-based liquid for simple integration into serums, lotions, and gels.
Synergistic Performance: Plays well with Niacinamide, Vitamin C derivatives, and Arbutin to target multiple pigmentation pathways.
Gentle & Effective: Suitable for daily-use products across diverse skin types.

Heading #1
Benefits	Brightening & Skin Lightening, Dark Spot Reduction, Even Skin Tone, Tyrosinase Inhibition
INCI Name	Aqua, Glycerin, Nonapeptide-1, Phenoxyethanol, Ethylhexylglycerin
Usage Rate	2%-5%
Active Type	Brightening Peptides, Peptides
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessPEP NON-1 sol.

The typical usage level is 2% to 5% in finished formulations, depending on desired intensity and product format.

Nonapeptide-1 competitively antagonizes α-MSH at the MC1R receptor on melanocytes. By blocking this initial signal, it helps inhibit tyrosinase activation and melanin synthesis, leading to a brighter, more even skin tone.

Yes. It is compatible with Niacinamide, Vitamin C derivatives, and Alpha-Arbutin for complementary, multi-pathway brightening. It also pairs well with AHAs to enhance penetration and visible results.

Formulate within pH 4.5 to 7.0 for optimal stability and performance.

When properly formulated, it is compatible with AHAs and retinoids. AHAs can help remove pigmented surface cells, supporting the appearance of a more even tone.

Yes, it is suitable across all skin tones to help address uneven pigmentation. It is synthetically produced and considered vegan and cruelty-free.

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