AccessPEP MM-634 Care

Advanced Dual-Peptide for Extracellular Matrix (ECM) Regeneration

INCI Name: Myristoyl Tetrapeptide-6, Myristoyl Tetrapeptide-34

AccessPEP MM-634 Care is an advanced anti-aging active featuring a synergistic complex of two biomimetic tetrapeptides. This dual-action ingredient works to rebuild the skin’s structural integrity by simultaneously stimulating the synthesis of crucial Extracellular Matrix (ECM) components like collagen and fibronectin, while also protecting existing proteins from enzymatic degradation. The myristoyl linkage enhances skin penetration, making it a highly effective solution for formulations targeting loss of firmness, wrinkles, and overall skin structure.

Solubility Notes:

Water-soluble. Add to the water phase or during the cool-down phase below 40°C (104°F). Stable between pH 4.0 and 7.0; compatible with hyaluronic acid, vitamin C derivatives, and antioxidants.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Firming & Lifting Serums

Delivers a concentrated dose of peptides to rebuild the dermal matrix, visibly improving skin density and facial contours.
Anti-Wrinkle Creams & Lotions

Integrates into daily moisturizers to progressively reduce the appearance of fine lines and deep-set wrinkles by reinforcing skin structure.
Collagen-Boosting Treatments

Ideal for targeted treatments that focus on stimulating collagen and fibronectin synthesis for plumper, more youthful-looking skin.
Neck & Décolleté Creams

Provides structural support to the delicate skin of the neck and chest, helping to combat sagging and crepey texture.
Age-Defense Night Creams

Works overnight to repair and regenerate the skin’s ECM, promoting a smoother and more resilient complexion by morning.
Eye Contour Creams

Gently firms and strengthens the skin around the eyes, helping to diminish the look of crow’s feet and improve elasticity.

Performance & Formulation Insights for AccessPEP MM-634 Care

How Dual-Peptide Action Rebuilds the Dermal Matrix

AccessPEP MM-634 Care employs a scientifically advanced two-pronged strategy to target the skin’s Extracellular Matrix (ECM)—the structural network responsible for firmness, elasticity, and overall resilience.

Stimulation of ECM Synthesis (Myristoyl Tetrapeptide-6): A biomimetic signal peptide that encourages fibroblasts to increase the production of structural proteins. It specifically upregulates Type I Collagen and Fibronectin, helping to densify and reinforce the dermal matrix.
Inhibition of ECM Degradation (Myristoyl Tetrapeptide-34): As skin ages, heightened Matrix Metalloproteinase (MMP) activity accelerates the breakdown of collagen. This peptide works to inhibit MMP-1, protecting existing collagen from enzymatic degradation and helping to prevent sagging and wrinkle formation.

The myristoyl (lipid) attachment enhances the peptides’ ability to penetrate the stratum corneum, improving bioavailability and ensuring they reach their intended cellular targets for maximum efficacy.

Formulation Guidelines

AccessPEP MM-634 Care is a user-friendly aqueous solution that integrates seamlessly into serums, creams, lotions, and gels. Add to the water phase or during the cool-down stage below 40°C (104°F) to preserve peptide integrity. The active is stable between pH 4.0 and 7.0 and is compatible with common anti-aging co-actives such as hyaluronic acid, vitamin C derivatives, and antioxidants.

Key Formulation Benefits

Dual-Action Efficacy: Combines ECM production and protection for comprehensive anti-aging results.
Enhanced Penetration: Myristoyl lipidation improves transcutaneous delivery and peptide bioavailability.
Clinically-Inspired Action: Mimics the skin’s natural regenerative signaling to improve firmness, elasticity, and wrinkles.
Excellent Formulation Compatibility: Easily incorporated into a wide range of water-based systems without compromising stability.
Targeted Structural Repair: Reinforces collagen and fibronectin networks for a visible lifting and firming effect.
High-Performance Anti-Aging: Addresses root causes of structural aging by rebuilding and preserving the ECM.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Collagen Boosting, Firming & Lifting, Wrinkle Reduction
INCI Name	Myristoyl Tetrapeptide-6, Myristoyl Tetrapeptide-34
Usage Rate	2%-10%
Active Type	Anti-Wrinkle Peptides, Peptides
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessPEP MM-634 Care

It combines two complementary peptides: Myristoyl Tetrapeptide-6 stimulates new collagen and fibronectin synthesis, while Myristoyl Tetrapeptide-34 helps inhibit MMP-1 to protect existing collagen. Together, they build and protect the ECM for more comprehensive anti-aging results.

The recommended usage level is 2% to 10%. For intensive firming or anti-wrinkle treatments, consider 5% to 10%.

Myristoyl denotes a myristic acid tail attached to the peptide (lipidation). This increases oil solubility and affinity with the skin’s lipid barrier, enhancing penetration and bioavailability.

Yes. AccessPEP MM-634 Care is stable from pH 4.0 to 7.0 and is compatible with most vitamin C derivatives. For AHA systems, ensure the final formula pH remains within the peptide’s stability range.

This complex addresses structural aging by rebuilding and preserving the ECM (collagen and fibronectin), improving firmness, density, and static wrinkles. Expression-line peptides (e.g., Acetyl Hexapeptide-8) target dynamic lines via neuromodulatory activity. They can be combined for a comprehensive approach.

The ECM is a network of proteins (such as collagen and elastin) and other molecules surrounding cells, providing structural and biochemical support. In skin, a robust ECM underpins firmness, elasticity, and a smooth appearance.

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