AccessPEP ATP-5 PWD

High-Performance Peptide for Reducing Eye Puffiness & Enhancing Elasticity

INCI Name: Acetyl Tetrapeptide-5

AccessPEP ATP-5 PWD is a high-purity Acetyl Tetrapeptide-5 powder designed for advanced anti-aging and eye care formulations. This potent peptide offers a dual-action approach: it effectively reduces under-eye puffiness by improving fluid dynamics and lymphatic circulation, while also fighting the effects of glycation to preserve skin elasticity and firmness. Its targeted mechanism makes it an essential ingredient for visibly diminishing eye bags, improving skin smoothness, and preventing premature aging.

Solubility Notes:

Water-soluble. Add to the water phase or during the cool-down phase, ensuring full dissolution (process below 40°C / 104°F where possible). Stable in formulations with pH 4.0–7.0.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Targeted Eye Creams & Serums

Provides a potent de-puffing effect, visibly reducing under-eye bags and improving the appearance of dark circles in concentrated treatments.
Anti-Aging Face & Neck Creams

Enhances overall skin elasticity and firmness by inhibiting glycation, helping maintain a smooth, youthful contour on the face and neck.
Hydrating & Firming Gels

Integrates into lightweight, water-based gels to deliver powerful anti-edema and skin-smoothing benefits without heavy emollients.
Brightening Eye Treatments

Helps reduce the appearance of shadows and dark circles linked to poor microcirculation and fluid retention for a brighter, rested look.
Contouring Body Lotions

Assists in reducing localized water retention and improving skin smoothness in firming and contouring body formulations.
Professional Sheet Masks

Delivers an intensive dose of the peptide in facial or eye masks for rapid de-puffing and smoothing results.

Performance & Formulation Insights for AccessPEP ATP-5 PWD

How Acetyl Tetrapeptide-5 Works

AccessPEP ATP-5 PWD targets two key pathways linked to visible aging around the eyes. First, it helps reduce edema (fluid accumulation) that contributes to under-eye puffiness by inhibiting Angiotensin I-Converting Enzyme (ACE). This action helps decrease vascular permeability and supports lymphatic drainage, promoting more efficient removal of excess fluid. Second, it provides strong anti-glycation activity. By protecting collagen and elastin from glycation-related stiffening, the peptide helps maintain the skin’s elasticity, firmness, and smooth appearance.

Formulation Guidelines

AccessPEP ATP-5 PWD is a high-purity, water-soluble powder that integrates seamlessly into serums, gels, and emulsions. Add to the water phase or during the cool-down phase below 40°C (104°F), ensuring complete dissolution before emulsification or final pH adjustment. It is stable across pH 4.0–7.0. Recommended usage is 1–3% for daily maintenance and 3–10% for targeted, intensive treatments.

Key Formulation Benefits

Clinically Proven De‑Puffing: Reduces the look of under-eye bags, with visible improvements often observed within 15 days.
Anti‑Glycation Power: Helps protect collagen and elastin from glycation-related damage to preserve elasticity and firmness.
Improves Skin Smoothness: Minimizes fluid retention and supports elasticity for a smoother, more refined texture.
Supports Microcirculation: Helps diminish the appearance of dark circles associated with congestion and fluid buildup.
Formulation‑Friendly Stability: Water-soluble and compatible in serums, gels, and emulsions within pH 4.0–7.0.
Targeted Action for Eye Care: Ideal for focused eye-area formulas where early signs of aging are most visible.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Eye Care, Skin Elasticity, Soothing & Anti-Inflammatory
INCI Name	Acetyl Tetrapeptide-5
Usage Rate	1%-10%
Active Type	Anti-Wrinkle Peptides, Peptides
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Powder
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessPEP ATP-5 PWD

Its primary function is to reduce puffiness and under-eye bags by addressing water retention (edema). It also helps improve skin elasticity by limiting the glycation of collagen and elastin.

The recommended usage range is 1–10%. Use 1–3% for daily or preventative formulas and 3–10% for intensive treatment serums and eye creams.

By supporting decongestion and microcirculation, it helps reduce fluid buildup and the shadows it creates under the eyes, improving brightness and overall appearance.

Yes. It works well with signal peptides (e.g., Palmitoyl Tripeptide-5) for collagen support and neurotransmitter-inhibiting peptides (e.g., Acetyl Hexapeptide-8) for comprehensive anti-aging eye care.

It remains stable and effective between pH 4.0 and 7.0.

Acetyl Tetrapeptide-5 is generally well tolerated, including on the delicate eye area. As with any active, a patch test is recommended.

Contact An Expert

Only 4 fields to get started. An expert will respond within 1 business day.

Your Samples Are Waiting

You've selected the following samples:

You haven't added any samples yet! Visit our product pages to select samples you'd like to request. Once you've added samples, return here to complete your request.

Ready to try them out?

Log In

Cookie Notice

The website uses cookies to ensure you get the best experience on our website. View our Privacy Policy to learn more.