AccessPEP AH8 PWD

High-Purity Anti-Wrinkle Peptide Powder for Expression Lines

INCI Name: Acetyl Hexapeptide-8

AccessPEP AH8 PWD is a high-purity, powder form of the clinically-proven anti-wrinkle peptide, acetyl hexapeptide-8. It effectively targets expression lines by inhibiting the SNARE complex, reducing the muscle contractions that lead to wrinkles on the forehead and around the eyes. The powder format allows for maximum formulation flexibility and potency, making it the ideal choice for creating concentrated, high-performance anti-aging serums, creams, and targeted treatments.

Solubility Notes:

Water-soluble. Dissolve in the water phase of your formulation. Stable within a pH range of 3.0-7.0.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

High-Potency Anti-Aging Serums

Enables the creation of concentrated, water-based serums that deliver a powerful dose of peptide for maximum wrinkle-smoothing effects.
Targeted Wrinkle Treatments

Perfect for spot treatments and correctors designed to specifically address deep expression lines on the forehead and between the brows.
Advanced Eye Creams

Safely and effectively reduces the appearance of crow's feet and fine lines in delicate eye contour formulations.
Age-Defense Moisturizers

Incorporates easily into daily-use emulsions and creams to provide continuous defense against the formation of dynamic wrinkles.
Professional Treatment Gels

Provides a potent active ingredient for lightweight gels and professional back-bar treatments for visible, fast-acting results.
Water-Free & Powder Formulations

The powder format is ideal for anhydrous or powder-based cosmetic systems where stability and concentration are critical.

Performance & Formulation Insights for AccessPEP AH8 PWD

How Acetyl Hexapeptide-8 Works

AccessPEP AH8 PWD functions as a biomimetic peptide, mimicking the N-terminal end of the SNAP-25 protein. In the skin, nerve cells communicate with muscles by releasing neurotransmitters, a process mediated by the SNARE protein complex. Acetyl hexapeptide-8 competes with SNAP-25 for a position within this complex, destabilizing it. This disruption reduces the release of neurotransmitters, leading to a decrease in the intensity of facial muscle contractions. By relaxing the muscles, the peptide effectively softens the appearance of dynamic wrinkles and expression lines, such as crow’s feet and forehead lines, offering a topical, non-invasive alternative for smoother skin.

Formulation Guidelines

As a high-purity powder, AccessPEP AH8 PWD offers excellent versatility. It is freely soluble in water and should be incorporated into the water phase of your formulation. For best results, pre-dissolve the powder in a portion of the water phase before combining it with other ingredients. It can be added at room temperature. This peptide is stable across a broad pH range of 3.0 to 7.0, making it compatible with a wide variety of cosmetic systems. Due to its high purity, only a small concentration is needed to achieve significant efficacy.

Key Formulation Benefits

High Purity & Potency: The powder form provides 100% active material, allowing for precise control over the final concentration in your formula.
Formulation Flexibility: Ideal for creating concentrated serums, gels, emulsions, and even anhydrous or powder-based products.
Clinically Proven Efficacy: Acetyl hexapeptide-8 is well-documented to visibly reduce the depth and length of expression wrinkles with consistent use.
Targeted Action: Specifically addresses wrinkles caused by facial movements, providing a focused approach to anti-aging.
Excellent Stability: Offers a long shelf life in its powder state and maintains stability within a wide formulation pH range.
Synergistic Potential: Combines effectively with other anti-aging actives, such as hydrating agents like hyaluronic acid and collagen-boosting peptides, to create comprehensive age-defying formulas.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Eye Care, Wrinkle Reduction
INCI Name	Acetyl Hexapeptide-8
Usage Rate	0.1%-2%
Active Type	Anti-Wrinkle Peptides, Peptides
Solubility	Water-Soluble
Application Area	Eye, Face
Physical Form	Powder
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessPEP AH8 PWD

The recommended concentration for this high-purity powder is between 0.1% and 2% in the final formulation, depending on the desired potency of the product.

The powder (PWD) version is 100% active peptide, offering formulators maximum control, potency, and the ability to create water-free formulations. Liquid versions are pre-dissolved solutions, which are easier to add but contain a lower active concentration and a specific preservative system.

AccessPEP AH8 PWD is water-soluble. It is best to dissolve the powder in the water phase of your formulation before adding other ingredients to ensure it is fully solubilized. It can be processed at room temperature.

It is stable down to a pH of 3.0. However, direct acids can sometimes interfere with peptide bonds. For maximum efficacy, it is often recommended to formulate at a pH above 4.0 or use encapsulated/stabilized forms of acids.

Acetyl hexapeptide-8 is most effective on dynamic or “expression” wrinkles, which are caused by repeated muscle movements (e.g., forehead lines, crow’s feet). It is less effective on static wrinkles caused primarily by sun damage and collagen loss.

Yes, AccessPEP AH8 PWD is a synthetic peptide produced without the use of any animal-derived ingredients, making it suitable for vegan formulations.

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