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AccessCARE RETINAL-S

1.0% Encapsulated Retinal for Faster Conversion and Clinically Demonstrated Results

INCI Name: Water, Butylene Glycol, Macadamia Ternifolia Seed Oil, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Glycerin, 1,2-Hexanediol, Cholesterol, Brassica Campestris (Rapeseed) Sterols, PEG-5 Rapeseed Sterol, Ceteth-3, Ceteth-5, Tocopherol, Aluminum/Magnesium Hydroxide Stearate, Potassium Cetyl Phosphate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate

AccessCARE RETINAL-S is a 1.0% Retinal active stabilized using the same 3-step encapsulation technology, designed for controlled release and efficient skin delivery. Retinal sits one conversion step closer to retinoic acid than Retinol, and RETINAL-S is engineered for faster conversion (~11× in comparative studies) alongside enhanced stability against heat and light. Clinical evaluation demonstrated 18-week wrinkle improvement and +9.4% dermal thickness improvement.

Solubility Notes:

Water-based liposomal dispersion; both/dual-soluble due to encapsulation. Incorporate into the water phase; protect from excessive heat and light during processing.

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Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

  • Clinically-Backed Anti-Aging Serums
    Supported by demonstrated 18-week wrinkle improvement and dermal thickness gains.
  • Fast-Acting Renewal Treatments
    ~11× faster conversion toward retinoic acid supports quicker-acting renewal claims versus standard retinol.
  • Retinol-Alternative/Upgrade Formulations
    Offers a more direct conversion pathway for brands positioning beyond entry-level retinol.
  • Firming & Dermal-Density Treatments
    +9.4% dermal thickness improvement supports firming and plumping claims.

Performance & Formulation Insights

How It Works: Retinal (retinaldehyde) is a Vitamin A conversion intermediate, requiring one fewer step to reach retinoic acid than Retinol. RETINAL-S applies the same 3-step encapsulation platform (LDH primary liposome → MLV secondary liposome → combined final encapsulation) to protect this reactive intermediate from heat and light while enabling controlled, efficient delivery. Comparative studies showed ~11× faster conversion toward retinoic acid, translating into clinically measured 18-week wrinkle improvement and +9.4% dermal thickness increase.

Formulation Guidelines

Dose based on the 1.0% Retinal concentration of the complex to reach your target finished-product Retinal percentage. Incorporate into the water phase; maintain standard Vitamin A handling precautions (protect from light/heat, opaque or airless packaging) despite encapsulation.

Key Formulation Benefits:

  • Faster Conversion: ~11× faster conversion toward retinoic acid in comparative studies.
  • Clinically Demonstrated Efficacy: 18-week wrinkle improvement and +9.4% dermal thickness improvement.
  • Enhanced Stability: Encapsulation protects against heat and light degradation.
  • Controlled, Efficient Delivery: Skin-mimetic MLV structures support efficient skin delivery.

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Benefits
Anti-Aging & Anti-Wrinkle, Firming & Lifting, Skin Elasticity, Wrinkle Reduction
INCI Name
Water, Butylene Glycol, Macadamia Ternifolia Seed Oil, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Glycerin, 1,2-Hexanediol, Cholesterol, Brassica Campestris (Rapeseed) Sterols, PEG-5 Rapeseed Sterol, Ceteth-3, Ceteth-5, Tocopherol, Aluminum/Magnesium Hydroxide Stearate, Potassium Cetyl Phosphate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
Usage Rate
1%-20%
Active Type
Vitamin A (Retinoids/Retinol), Vitamins & Derivatives
Solubility
Both/Dual-Soluble
Application Area
Face
Physical Form
Liquid/Solution
Certifications

Frequently Asked Questions About AccessCARE RETINAL-S

Retinal requires one fewer conversion step to reach retinoic acid, and RETINAL-S showed ~11× faster conversion in comparative studies.
18-week wrinkle improvement and +9.4% dermal thickness improvement were demonstrated in clinical evaluation.
Dose based on the 1.0% Retinal concentration of the complex to reach your target finished-product Retinal percentage.

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AccessCARE RETINAL-S

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