AccessCARE GSH

High-Performance Antioxidant for Skin Brightening and Detoxification

INCI Name: Glutathione

AccessCARE GSH is a high-purity, powdered form of Glutathione, the body’s master antioxidant essential for cellular defense and skin health. This powerful tripeptide protects mitochondria from oxidative damage, detoxifies the skin from urban pollutants, and promotes a brighter, more even complexion by inhibiting melanin synthesis. It also regenerates other key antioxidants like Vitamins C and E, making it a cornerstone ingredient for advanced anti-aging, brightening, and pollution defense formulations.

Solubility Notes:

Water-soluble. Add to the water phase during the cool-down process (below 40°C / 104°F) to maintain stability.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Brightening Serums & Treatments

Effectively reduces the appearance of dark spots and hyperpigmentation for a more luminous, even skin tone.
Anti-Pollution Skincare

Protects skin from environmental stressors and neutralizes free radicals caused by pollution, UV exposure, and blue light.
Detoxifying Face Masks

Helps purify and rejuvenate stressed, dull skin by supporting its natural detoxification pathways.
Antioxidant Booster Products

Enhances the efficacy and stability of Vitamins C and E in daily moisturizers and anti-aging complexes.
Under-Eye Creams

Targets oxidative stress that can contribute to dark circles, helping to brighten the delicate skin around the eyes.
Night Repair Creams

Supports the skin's natural repair and regeneration processes overnight, combating daily damage for a refreshed appearance.

Performance & Formulation Insights for AccessCARE GSH

How Glutathione Works as a Master Antioxidant

Glutathione is a tripeptide naturally found in every cell of the human body, where it serves as the primary defense against oxidative stress. Its mechanism of action is multifaceted. First, it directly neutralizes damaging free radicals. Second, and more importantly, it regenerates other essential antioxidants, such as Vitamin C and Vitamin E, bringing them back to their active, protective state. For skin brightening, Glutathione intervenes in the melanin production pathway by inhibiting the tyrosinase enzyme and shifting melanin synthesis from the darker eumelanin to the lighter pheomelanin, resulting in a visible lightening effect and a more uniform skin tone.

Formulation Guidelines for Optimal Stability

AccessCARE GSH is a fine white powder that is readily soluble in water. For maximum stability and efficacy, it should be added to the water phase of a formulation during the cool-down stage, at temperatures below 40°C (104°F). Glutathione performs best in formulations with a slightly acidic to neutral pH, ideally between 4.0 and 6.0. In aqueous solutions, Glutathione can be prone to oxidation, so it is highly recommended to formulate it alongside other antioxidants (like Vitamin C and Ferulic Acid) and a chelating agent (such as Disodium EDTA) to ensure its long-term stability and performance in the final product.

Key Formulation Benefits

Potent Antioxidant Defense: Provides exceptional protection against oxidative stress from environmental aggressors, preserving skin health and vitality.
Clinically Recognized Brightening: Effectively lightens the skin and reduces hyperpigmentation by inhibiting the key enzyme in melanin production.
Synergistic Power: Boosts the performance and stability of other antioxidants, particularly Vitamins C and E, creating a more powerful and comprehensive defense system.
Detoxifying Action: Helps protect skin cells from damage caused by urban pollutants, heavy metals, and other environmental toxins.
Improves Skin Clarity: Promotes a clear, radiant complexion by reducing the impact of stress-induced damage and supporting cellular health.
High-Purity Powder: Easy-to-use powder form allows for precise, controlled dosing and avoids the stability issues of pre-dissolved solutions.

Heading #1
Benefits	Antioxidants, Brightening & Skin Lightening, Dark Spot Reduction, Pollution Defense, Tyrosinase Inhibition
INCI Name	Glutathione
Usage Rate	0.5%-3%
Active Type	Amino Acids & Derivatives, Glutathione
Solubility	Water-Soluble
Application Area	Body, Eye, Face
Physical Form	Powder
Certifications	Cruelty-Free, Halal, Kosher, Vegan

Frequently Asked Questions About AccessCARE GSH

The recommended usage rate is between 0.5% and 3.0%, depending on the desired efficacy and product application. For daily antioxidant protection, 0.5-1% is effective, while 1-3% is recommended for intensive brightening and treatment products.

Glutathione brightens the skin through a dual-action mechanism: it inhibits the activity of tyrosinase, the enzyme required for melanin production, and it shifts the type of melanin produced from the dark brown/black eumelanin to the lighter yellow/red pheomelanin.

Yes, it is highly recommended. Glutathione and Vitamin C have a synergistic relationship where they regenerate each other, enhancing the stability and antioxidant capacity of the entire formulation.

To ensure stability and bioavailability, formulations containing AccessCARE GSH should be maintained within a pH range of 4.0 to 6.0.

AccessCARE GSH should be dissolved in the water phase during the cool-down step (below 40°C / 104°F) and after any high-shear mixing to prevent degradation.

Absolutely. Its powerful antioxidant and detoxifying properties make it an ideal active ingredient for products designed to protect the skin from damage caused by urban pollutants and environmental stressors.

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