AccessCARE CERA MLS-45

Q: What is the recommended usage rate for AccessCARE CERA MLS-45?

For daily skincare and maintenance, a concentration of 1–3% is recommended. For intensive barrier repair, very dry skin, or post-procedure products, use 3–5%.

Q: Why is a multi-ceramide complex with cholesterol better than using a single ceramide?

The skin’s lipid barrier is a complex mixture of multiple ceramides, cholesterol, and fatty acids in a specific ratio. A multi-ceramide complex that includes cholesterol is biomimetic, more accurately replicating the skin’s natural composition for more effective, holistic barrier repair.

Q: Can this ceramide complex be used in products for acne-prone skin?

Yes. A compromised skin barrier can contribute to acne. By restoring barrier function without being heavy or occlusive, this complex can help balance the skin. However, final formulation comedogenicity should be evaluated.

Q: What is the optimal pH range for formulations containing AccessCARE CERA MLS-45?

This complex performs best and remains stable in formulations with a pH range of 4.5 to 7.0.

Q: How should I incorporate this ingredient into my formula?

Add AccessCARE CERA MLS-45 to the water phase of your formulation or during the cool-down phase when the temperature is below 40°C (104°F). Use gentle agitation to ensure even dispersion.

Q: Is AccessCARE CERA MLS-45 derived from animal sources?

No. The components are derived from vegetable and synthetic sources, making it suitable for vegan formulations.

Biomimetic Multi-Lamellar Ceramide Complex for Advanced Barrier Repair

INCI Name: Ceramide EOP, Ceramide NS, Ceramide NP, Ceramide AS, Ceramide AP, Hydrogenated Lecithin, Cholesterol, Glyceryl stearate, 2,3-Butanediol

AccessCARE CERA MLS-45 is a skin-identical, multi-lamellar ceramide concentrate designed for advanced skin barrier restoration. Featuring a comprehensive blend of five essential ceramides (EOP, NS, NP, AS, AP) plus cholesterol and hydrogenated lecithin, this complex precisely mimics the natural lipid structure of the stratum corneum. It effectively replenishes depleted skin lipids, reduces transepidermal water loss (TEWL), and soothes sensitive or compromised skin, making it a cornerstone active for high-performance moisturizers and anti-aging treatments.

Solubility Notes:

Water-dispersible. Add to the water phase of your formulation or during the cool-down phase below <40°C.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Barrier Repair Creams & Lotions

Forms the structural foundation of restorative formulations to rebuild and maintain a healthy, resilient skin barrier.
Moisturizers for Dry & Sensitive Skin

Delivers deep, long-lasting hydration and reduces irritation by reinforcing the skin's protective lipid matrix.
Anti-Aging Serums & Treatments

Improves skin elasticity and smooths texture by replenishing the essential lipids that decline with age.
Post-Treatment Skincare

Soothes and repairs skin following exfoliation, chemical peels, or environmental stress, accelerating recovery.
Hand & Body Care

Provides intensive moisture and protection for chronically dry areas like hands, elbows, and feet.
Hydrating Toners & Essences

Easily incorporates into lightweight aqueous formulas to deliver foundational barrier support and help prevent dehydration.

Performance & Formulation Insights for AccessCARE CERA MLS-45

How This Biomimetic Complex Restores Skin Barrier

AccessCARE CERA MLS-45 works by replenishing the skin’s intercellular lipid matrix, which is crucial for a healthy barrier. The stratum corneum is often described with a “brick and mortar” analogy, where skin cells (corneocytes) are the bricks and the lipid matrix is the mortar. This “mortar” is primarily composed of ceramides, cholesterol, and free fatty acids. AccessCARE CERA MLS-45 delivers a skin-identical blend of these critical components in a multi-lamellar structure that mimics the skin’s own organization. This biomimetic structure allows the active to integrate seamlessly into the skin, reinforcing the mortar, sealing gaps between cells, and significantly reducing transepidermal water loss (TEWL). The result is a stronger, more hydrated, and less reactive skin barrier.

Formulation Guidelines & Technical Advantages

AccessCARE CERA MLS-45 is a user-friendly liquid dispersion designed for easy incorporation into emulsions and water-based systems. For optimal results, add it to the water phase of your formulation or during the cool-down phase at temperatures below 40°C (104°F) using gentle mixing. It is stable within a typical cosmetic pH range of 4.5 to 7.0. This complex is highly compatible with other common cosmetic actives, including hyaluronic acid, niacinamide, peptides, and botanical extracts, allowing for the creation of powerful, multi-functional products. Recommended usage rates are 1–3% for daily maintenance and up to 5% for intensive repair or treatment products.

Key Formulation Benefits

Advanced Barrier Repair: Contains five key ceramides plus cholesterol to provide a comprehensive, skin-identical solution for restoring barrier integrity.
Reduces TEWL: Clinically shown to reduce transepidermal water loss, locking in moisture for long-lasting hydration and preventing dryness.
Multi-Lamellar Structure: Organized lipid layers mimic the skin’s natural structure, helping ensure superior performance versus single ceramides.
Soothes Sensitive Skin: Helps calm visible signs of sensitivity and irritation by strengthening the skin’s natural defenses.
Improves Skin Texture & Elasticity: Replenishes essential lipids to support smoother feel, improved firmness, and a more youthful look.
Easy to Formulate: Supplied as a water-dispersible liquid for straightforward processing and homogeneous distribution in finished products.

Heading #1
Benefits	Anti-Aging & Anti-Wrinkle, Barrier Repair, Deep Hydration, Moisturizing & Hydration, Skin Elasticity, Soothing & Anti-Inflammatory
INCI Name	Ceramide EOP, Ceramide NS, Ceramide NP, Ceramide AS, Ceramide AP, Hydrogenated Lecithin, Cholesterol, Glyceryl stearate, 2,3-Butanediol
Usage Rate	1%-5%
Active Type	Ceramide Complexes, Ceramides & Lipids
Solubility	Water-Soluble
Application Area	Body, Eye, Face, Lip
Physical Form	Liquid/Solution
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessCARE CERA MLS-45

For daily skincare and maintenance, a concentration of 1–3% is recommended. For intensive barrier repair, very dry skin, or post-procedure products, use 3–5%.

The skin’s lipid barrier is a complex mixture of multiple ceramides, cholesterol, and fatty acids in a specific ratio. A multi-ceramide complex that includes cholesterol is biomimetic, more accurately replicating the skin’s natural composition for more effective, holistic barrier repair.

Yes. A compromised skin barrier can contribute to acne. By restoring barrier function without being heavy or occlusive, this complex can help balance the skin. However, final formulation comedogenicity should be evaluated.

This complex performs best and remains stable in formulations with a pH range of 4.5 to 7.0.

Add AccessCARE CERA MLS-45 to the water phase of your formulation or during the cool-down phase when the temperature is below 40°C (104°F). Use gentle agitation to ensure even dispersion.

No. The components are derived from vegetable and synthetic sources, making it suitable for vegan formulations.

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