AccessCARE CERA AC-45

High-Potency 5-Ceramide Complex for Advanced Barrier Repair

INCI Name: Ceramide EOP, Ceramide NS, Ceramide NP, Ceramide AS, Ceramide AP, Hydrogenated Lecithin, Cholesterol, Glyceryl stearate, Dipropylene glycol

AccessCARE CERA AC-45 is a powerful, biomimetic ceramide complex featuring an exceptionally high concentration (40%) of five essential ceramides (EOP, NS, NP, AS, AP). This scientifically balanced blend includes cholesterol and hydrogenated lecithin to mimic the skin’s natural lipid structure, enabling superior barrier restoration and moisture retention. Ideal for formulations targeting dry, compromised, or sensitive skin, it delivers deep hydration and structural repair.

Solubility Notes:

Oil-dispersible paste. Incorporate into the oil phase or during the cool-down phase of an emulsion below 50°C (122°F). Recommended finished product pH: 5.0–7.0.

Perfect For These Applications

Other cosmetic uses possible—contact us for formulation guidance.

Barrier Repair Creams

Provides the structural lipids necessary to rebuild a compromised skin barrier, reducing trans-epidermal water loss (TEWL) and soothing irritation.
Sensitive Skin Formulations

Replenishes essential lipids to calm sensitive or reactive skin, strengthening its resilience against environmental stressors.
Anti-Aging Moisturizers

Restores the lipid foundation of mature skin, improving firmness, hydration, and overall texture for a smoother appearance.
Night Repair Products

Works overnight in rich creams and balms to deeply replenish the skin's lipid matrix while it is in its natural regenerative state.
Body Lotions for Dry Skin

Effectively treats and helps prevent extreme dryness and flakiness in body care products, including for eczema-prone skin.
Protective Hand Creams

Restores the barrier function of frequently washed or sanitized hands, helping prevent cracking and dryness.

Performance & Formulation Insights for AccessCARE CERA AC-45

How a Multi-Ceramide System Restores Skin

The skin’s outermost layer, the stratum corneum, relies on a complex lipid matrix to function as an effective protective barrier. This matrix is primarily composed of ceramides, cholesterol, and fatty acids arranged in a highly organized lamellar structure. AccessCARE CERA AC-45 is a biomimetic active designed to replicate this natural composition. By delivering a synergistic blend of five key ceramide types (EOP, NS, NP, AS, AP) alongside cholesterol and hydrogenated lecithin, it integrates into the skin’s lipid layers to help rebuild gaps in the barrier. This action locks in moisture, reduces water loss, and shields the skin from external irritants and allergens—supporting a stronger, more resilient, and healthier-looking skin barrier.

Formulation Guidelines

AccessCARE CERA AC-45 is a high-viscosity, oil-dispersible paste designed for easy incorporation into emulsions. For optimal results, add it to the oil phase of your formulation. Alternatively, incorporate during the cool-down phase after emulsion formation, ensuring the temperature remains below 50°C (122°F) to preserve the lipid structure. Use gentle, steady mixing to achieve uniform dispersion. The optimal pH range for finished formulations is 5.0–7.0. By restoring a healthy barrier, this system can also enhance the performance and bioavailability of other actives in your formula.

Key Formulation Benefits

High-Potency Active: Contains an exceptionally high 40% concentration of five essential ceramides for maximum efficacy at low usage rates.
Biomimetic Composition: Precisely mirrors the skin’s natural lipid ratio of ceramides and cholesterol for superior integration and performance.
Clinically Relevant Outcomes: Helps reduce trans-epidermal water loss (TEWL), boosts hydration, and soothes dry, compromised skin.
Enhanced Skin Feel: Contributes to a smooth, nourished, non-greasy sensory in creams and lotions.
Formulation Versatility: Ideal for daily moisturizers, serums, and intensive treatments for face, body, and hands.
Improves Skin Resilience: Strengthens the skin’s defenses against environmental aggressors, allergens, and irritants.

Heading #1
Benefits	Barrier Repair, Deep Hydration, Moisturizing & Hydration, Soothing & Anti-Inflammatory
INCI Name	Ceramide EOP, Ceramide NS, Ceramide NP, Ceramide AS, Ceramide AP, Hydrogenated Lecithin, Cholesterol, Glyceryl stearate, Dipropylene glycol
Usage Rate	1%-5%
Active Type	Ceramide Complexes, Ceramides & Lipids
Solubility	Oil-Soluble
Application Area	Body, Face
Physical Form	Gel
Certifications	Cruelty-Free, Vegan

Frequently Asked Questions About AccessCARE CERA AC-45

The recommended usage rate is 1% to 5%, depending on the desired level of barrier repair and moisturization for the target application.

Different types of ceramides perform distinct structural roles within the skin barrier. A complex of five ceramides provides a more comprehensive and effective approach to barrier repair, mimicking the natural diversity of lipids found in healthy skin.

Yes. To preserve the delicate lipid structure, incorporate AccessCARE CERA AC-45 into the oil phase or during the cool-down phase of your emulsion, keeping the temperature below 50°C (122°F).

For maximum stability and efficacy, maintain the final formulation pH between 5.0 and 7.0.

Yes. As an oil-dispersible paste, it is suitable for anhydrous formulations like balms, ointments, and oil-based serums to provide intensive barrier support.

By restoring a healthy, intact skin barrier, this ceramide complex supports overall skin function and can enhance the penetration and bioavailability of other active ingredients.

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