High-Potency 7-Ceramide Complex with PSLN Nano-Encapsulation for Deep Barrier Repair
Performance & Formulation Insights
How It Works: CERA 45T8’s seven-ceramide architecture mirrors the diversity of ceramide subtypes naturally found in the stratum corneum, rather than relying on a single ceramide species. PSLN technology addresses a core formulation challenge with ceramides — their poor solubility — by nanoizing the complex at high concentration and surrounding it with a phospholipid matrix, which helps prevent agglomeration, separation, and precipitation while improving skin absorption depth.
Formulation Guidelines
Use at 0.01–10.00% depending on claim level; even low use rates (0.01–1%) can contribute measurable barrier benefits due to the high 45% actives loading. Incorporate into the water phase or during cool-down with moderate mixing.
Key Formulation Benefits:
- Comprehensive Barrier Support: Seven ceramide types plus glycosphingolipids address multiple barrier-function pathways in one ingredient.
- Improved Skin Moisture: Supports visible improvement in hydration and moisture retention.
- Enhanced Skin Absorption & Depth: PSLN encapsulation improves delivery into deeper skin layers versus non-encapsulated ceramides.
- Low Use-Level Efficiency: High 45% concentration allows effective dosing even at low inclusion rates.